Genetics Course Page Fall 2018

Minot State University

Genetics/ Biol 215

Course Page

Fall 2018

 

Announcements
Complete F2 data HERE
 
Points--grade calculator updated 12-2-2018
 
Point total as of 12-2-2018= 386.  Anticipated total points = ~516.
 

Lectures

Lecture 1

Lecture 2

Lecture 3

Lecture 4

Lecture 5

Lecture 6

Lecture 7

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Lecture 8

Lecture 9

Lecture 10

Lecture 11

Lecture 12

Lecture 13

Lecture 14

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Lecture 15

Lecture 16

Lecture 17

Lecture 18

Lecture 19

Lecture 20

Lecture 21 (See X-inactivation paper below)

Lecture 22

Lecture 23

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Lecture 24

Lecture 25

Lecture 26

Lecture 27

Lecture 28

Lecture 29

Lecture 30

Lecture 31

Lecture 32

Lecture 33 (replication animations below)

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Lecture 34 (see PV29 gels in lab section)

Lecture 35

Lecture 36

Lecture 37

Animations

Mitosis

Meiosis

Replication 1

Replication 2

 

 

 

 

Lecture Documents/Assigned Reading

Syllabus  Fall 2018

lecture summary page

Paper 1---Genetically engineering animals for human health

Paper 2--Down syndrome

Paper 3 Dog gentetics paper

Paper 4--Variation in size in dogs--read abstract.

Paper 5---X-inactivation molecular mechanism

 

Exam Prep

Topics lists

Exam 1 topics list

Exam 2 topics list

Exam 3 topics list

Exam 4 topics list

Practice Problems

Problem Set 1.  Problem set 1 Key

Problem Set 2  Problem set 2 key

Pedigree problems--including X-linkage (For exam 2, just look at autosomal recessive and autosomal dominant traits displayed by pedigrees). 

Problem set 3---Many similar practice problems in the text---try colored boxes in the chapters.   Problem set 3 key.

Hemophilia story--questions

Problem Set 4--linkage/recombination mapping.   Linkage problems answers

 

Lab

LAB SYLLABUS

lab report guidelines

Preparation for Lab 1--Part 1

Preparation for Lab 1--Part 2

Lab 1---Chromsomes and Mitosis

Pointers for first lab report

Example lab report

Lab 2---Meiosis Part 1

Lab 2---Meiosis Part 2

MEIOSIS POWERPOINT CLICK HERE 

Lab 3--Mendel Part 1

Lab 4--Analyisis of corn data           Compiled Data HERE              Guidelines for lab 3-4

Lab 5--Human traits (We will return to more population analysis soon)

Lab 6--Introduction to Drosophila   Introductory lecture

Lab 7---Analyisis of human traits---Population genetics.  Hardy-Weinberg. 

Lab 5/7 guidelines    Human traits data

Lab 8--DNA--The "transforming principle"

Setting up F1 X F1 crosses---Drosohila part II

Lab 8--Observations and discussion.       Gene regulation presentation.    GFP assignment

Lab 9--Determining you genotype for PV92 "gene".  Polymerase Chain Reaction. (Lab handout says lab 10).   PCR LECTURE

Drosophila F2 data analysis--guidelines

Lab 9 part 2---analysis of PCR products.  It is essential that you are prepared for this lab.  Read your lab handout from Lab 10- Part 1 to refresh your memory of PCR and to begin to understand the dimorphic nature of the PV92 locus.  PV92 has 2 alleles. Predict  your genotype.  Review animation on electrophoresis. 

Electrophoresis animation: http://www.youtube.com/watch?src_vid=0x2Lh5Rq8e0&annotation_id=annotation_299771&feature=iv&v=v0sJRZATXEA

PV92 gels here.  9 am lab     1 pm lab

 

 

Complete fly data HERE

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Below this line---Ignore!  Old material

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    Corn data: here 

Lab 5 ---Varaiation in Drosophila/X-linked genes/Chromsome mapping

 

Lab 7--gene pool/population genetics

Lab 8--Bacterial transformation "seeing the genetic material at work"  Transformation discussion--Here

Lab 9---Determinining your PV92 genotype---PCR and genetic polymorphisms.  PCR LECTURE

 

Gel pictures HERE

 

 

 

 

 

 

(optional reading) 

 

Lab 6---Drosophila part I

Lab 7---take home lab on Polygenic/Continuous traits

Lab 8---Drosophila part II and Introduction to recombination mapping Part I and Part II.

Lab 9---Bacterial transformation---"seeing" the genetic material.

Lab 10 Transformation data and  discussion questions  AND Drosophila Part III 

Lab 11--Polymerase Chain Reaction--determining your PV92 genotype  

 

http://www.youtube.com/watch?src_vid=0x2Lh5Rq8e0&annotation_id=annotation_299771&feature=iv&v=v0sJRZATXEA

100 bp ladder

1 kb ladder

 

View Animation---Transcription (prokaryotes) and more Transcription (eukaryotes)

 

Protein Synthesis Animation--translation

animations---translation

Electrophoresis animation: http://www.youtube.com/watch?src_vid=0x2Lh5Rq8e0&annotation_id=annotation_299771&feature=iv&v=v0sJRZATXEA

 

 

 

Problem sets/questions

problem set 1

Ch. 2 multiple choice

Problem set 2    Problem set 2 

---Fly data here!

Lab 1  Mitosis  documents

Lab 2-- Meiosis Part 1

 

 

 

 

 

Lab 3-4 report guidelines

Lab 5 materials--Drosophila part 1

 

Lab 7--Human traits in a population/understanding gene/allele pool

Guidelines for Lab 6-7 report

Lab 8---  We will be studying a polygenic/quantitative human trait related to fingerprints.

Lab 9---Molecular genetics--Bacterial transformation  After overnight incubation please use this handout to observe your plates.  

Lab 10--Polymerase Chain Reaction--determining your PV92 genotype

 

 

PCR

 

 

 

 

Problem Set 3    Problem set 3 key/answer

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AttachmentSize
National Geo dog genetics story.pdf3.66 MB
guidelinesforfinal-1.doc25.5 KB
Lecture 25-2017.pptx1.22 MB
SKM_368e18090911500.pdf320.3 KB
down syndrom jbc 2015.pdf742.85 KB
Lecture 37-2018 Fall.ppt3.12 MB